Abstract
Neurofibromatosis type 1 (NF1) is an autosomal dominant inherited affection characterized by a higher chance of development of tumors. There have been only few cases of glioblastoma (GBM) in adult NF1 patients. In this paper, we present the case of 43 years old patient who presented initially amnesia and seizures. The patient underwent gross total surgical excision, followed by the Stupp protocol. He received concomitant chemo-radiotherapy with temozolomide then adjuvant temozolomide chemotherapy. We have also reviewed the literature and reported the cases of GBM in NF1 patients previously published.
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