Glial and Melanocytic Tumors of the Retina and Optic Disc

Abstract

In this review, solitary limited retinal astrocytic proliferation, retinal astrocytic hamartoma, acquired retinal astrocytoma, optic disc melanocytoma and optic disc melenoma, which are glial and melanocytic tumors of the retina and optic disc, are discussed. The point that makes these diseases important is the necessity of making the differential diagnosis. Because while there are retinal tumors that can show complete regression in this group of diseases, there are also tumors where more severe clinical conditions can be seen that can lead to vision loss and even systemic metastatic spread. In addition, serious retinal and optic nerve complications can be observed in some tumors, which can lead to vision loss. Another important point is the malignant transformation that can be observed in tumors such as melanocytoma, although it is rare. For this reason, periodic follow-up of these cases in the presence of an experienced ophthalmologist is very important. This review aimed to summarize the clinical and histopathological features that may be important in the diagnosis and follow-up of these tumors.