Abstract
Glandular odontogenic cysts are rare odontogenic cysts with a wide range of histopathological features. In this paper we describe the clinical and pathological features of an unusual case of a glandular odontogenic cyst with metaplastic cartilage. The previous literature of odontogenic cysts presenting with metaplastic cartilage is reviewed alongside a discussion of the differential diagnoses. To our knowledge this is the first reported case of a glandular odontogenic cyst with metaplastic cartilage.
Highlights
Glandular odontogenic cyst was first described by Padayachee and van Wyk in 1987 as a “sialo-odontogenic cyst”[1]
Gardner et al [2] re-named the cyst as a glandular odontogenic cyst (GOC) due to the lack of evidence of a salivary origin and this nomenclature was subsequently accepted by the World Health Organisation [3]
GOC is a rare odontogenic cyst, with a demographic study showing they only account for 0.2% of odontogenic cysts within a UK population [4]
Summary
Glandular odontogenic cyst was first described by Padayachee and van Wyk in 1987 as a “sialo-odontogenic cyst”[1]. GOC is a rare odontogenic cyst, with a demographic study showing they only account for 0.2% of odontogenic cysts within a UK population [4] It occurs over a wide age range, with most cases diagnosed in the 5–7th decade with no gender predilection [5]. Examination of the cyst lining showed the stratified squamous epithelium to be of variable thickness with focal plaque like thickenings (Fig. 3a). Given the clinically extensive swelling, presence of cartilage and to rule out higher risk pathology the lesion was reviewed by specialist musculoskeletal pathologists. They agreed the cartilage was metaplastic in appearance. A final diagnosis of a GOC with metaplastic cartilage was made
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