Ginseng Oral Liquid Enhances Therapeutic Output of Rotigotin Patch Plus Amantadine in Parkinson’s Disease

Abstract

Transdermal patches of rotigotine, a dopamine agonist of the non-ergoline class, are used to treat the signs and symptoms of Parkinson’s disease. In this study, we have probed the effect of ginseng oral liquid on the efficacy of the rotigotin patch plus amantadine in treating Parkinson’s disease. Measurements of mental behavior, daily activities, and motor function were used to calculate the total effective rate of the treatment that was elevated in the presence of ginseng oral liquid. While ginseng oral liquid lowered the Parkinson’s Disease Questionnaire scores and levels of serum amyloid A and interleukin-12, it augmented apolipoprotein A1. No difference was seen in the incidence of adverse events between the two groups. To sum up, rotigotin patches in association with amantadine and ginseng oral liquid are effective in treating Parkinson’s disease, which can effectively promote the quality of life of patients, decrease clinical symptoms, and reduce inflammatory reactions.