Abstract
Pleomorphic lipoma is a rare, benign, pseudosarcomatous, soft-tissue neoplasm that typically involves the subcutis of the posterior neck, upper back, and shoulders. Pleomorphic lipoma is a variant of spindle cell lipoma, and these two types of lipoma exhibit similar histological fea- tures and immunophenotypes. Rarely can it be cutaneous manifestation of a paraneoplastic syndrome. We report a case of long standing multiple lipomas in an elderly female with a rare genodermatoses (lamellar icthyosis). Presentation was of a wellcircumscribed subcutaneous mass. Associated functional limitation of the affected shoulder was seen. Complete surgical excision with acceptable cosmosis was achieved. Histopathology revealed pleomorphic lipoma.
Highlights
IntroductionSpindle cell lipoma and pleomorphic lipoma represent a distinct entity grouped under the term “atypical lipoma”[1]
Pleomorphic lipoma is a rare variant of lipoma
Cytology shows admixture of atypical cells and multinucleated giant cells characterised by multi ple, pleomorphic, hyperchromatic nuclei arranged in peripheral wreath like fashion with a dense cytoplasm
Summary
Spindle cell lipoma and pleomorphic lipoma represent a distinct entity grouped under the term “atypical lipoma”[1]. Pleomorphic lipoma is a rare variant of lipoma. It is typically seen in men in the age group of 45-60 years and commonly arises in neck and shoulder region. Cytology shows admixture of atypical cells and multinucleated giant cells characterised by multi ple, pleomorphic, hyperchromatic nuclei arranged in peripheral wreath like fashion with a dense cytoplasm. The diagnosis is often misleading towards malignancy[2]. This tumor is benign and treatment is complete excision. We report a 65 year old lady with genodermatoses and pleomorphic lipoma over the back and axilla treated with complete excision of the tumor
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