Giant Lymph Node Hyperplasia of the Hyaline Vascular Type with Plasmacytoid T-Cells and Presentation in Infancy

Abstract

Giant lymph node hyperplasia is uncommon in children and is exceptionally rare in infancy. The authors report a case of giant lymph node hyperplasia that presented as a right supraclavicular mass in an asymptomatic two-month-old female infant. Clinically, the mass was thought to be either a lipoma or a cystic hygroma, and it was followed for more than two years before excision. Histologically, the tumor showed classic features of giant lymph node hyperplasia of the hyaline vascular type but also showed many clusters of plasmacytoid T-cells.