Giant Endometrial Polyp in a Postmenopausal Woman.

Vivek Nair,Biswajit Dey,Ashok Singh,Jyotsna N Bharti,Jitendra S Nigam

doi:10.7759/cureus.12789

Abstract

Endometrial polyps are the benign localized overgrowth of endometrial tissue composed of a variable amount of gland, fibroblast-like spindle cells stroma, and thick-walled blood vessels. They develop as a result of unbalanced estrogens and progestin. Polyps greater than 4 cm are considered giant polyps. We report a case of giant endometrial polyp in a postmenopausal woman who presented with postmenopausal bleeding without any history of hormone or drug intake. However, the possible cause may be the age and use of phytoestrogens in the daily routine diet for a long time.

Highlights

Endometrial polyps are the benign localized overgrowth of endometrial tissue composed of a variable amount of gland, fibroblast-like spindle cells stroma, and thick-walled blood vessels
We report a case of giant endometrial polyp in a postmenopausal woman who presented with postmenopausal bleeding without any history of hormone or drug intake
We report the case of a giant Endometrial polyps (EPs) in a postmenopausal woman who presented with postmenopausal bleeding without any history of hormone or drug intake

Summary

Introduction

Endometrial polyps (EPs) are the benign localized overgrowth of endometrial tissue protruding into the uterine cavity, affecting approximately 25% of women [1,2]. Long-term consumption of PEs can act like estrogen, causing an unbalance between estrogen and progestin, leading to uterine pathologies such as endometrial hyperplasia or EP [1]. A pedunculated polypoidal mass with a thin stalk attached to the fundus area, measuring 7 × 4 × 4 cm, was seen in the endometrial cavity. A histopathological diagnosis of simple endometrial hyperplasia for age with benign hyperplastic EP was made. Further history was elicited from the patient for the possible etiology She gave a history of daily intake of turmeric, garlic, ginger, onion, and the occasional intake of thyme and soybean in her diet, which are rich in PEs. Based on the clinical and histopathological findings, a final diagnosis of benign hyperplastic EP probably caused by the long-term dietary intake of PEs was made. The postoperative period was uneventful and the patient was doing well after six months of follow-up

Discussion

Findings

Disclosures