Abstract
human. The SIS valve is intended to replace venous valves that are destroyed during thromboph!ebitis or incompetent from birth. We expect the SIS valve will be remodeled with recipient's own cells and will function without need for continuous bloodthinning medications. Possible applications indude: 1. Chronic venous insllfficiency; 2. Varicoceles in males; 3. Ovarian and pelvic varices; 4. Failed conduits from right ventride to the pulmonary artery. Although a great deal of work remains to be done, these early results show that the development of a biological prosthetic venous valve for transcatheter placement is more than just feasible.
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