Abstract
Ultrasound is an integral part of obstetric practice, and assessment of gestational age (GA) is a central element of obstetric ultrasonography. Sonographic estimation of GA is derived from calculations based on fetal measurements. Numerous equations for GA calculation from fetal biometry have been adopted in routine practice. This study reports a new method of estimating GA in the second and third trimester using interischial distance (IID), the distance between the two ischial primary ossification centers, on fetal ultrasound. Four hundred women with uncomplicated normal singleton pregnancies from 16 weeks to term were examined. Standard fetal obstetric ultrasound was done measuring biparietal diameter (BPD) and femur length (FL) for each fetus. The IID, in millimeters, was correlated with the GA in weeks based upon the BPD and FL individually, and the BPD and FL together. Statistical analysis showed strong correlation between the IID and GA calculated from the FL with correlation coefficient (r =0.989, P<0.001). Strong linear correlation was also found between the IID and GA based upon BPD and BPD+FL. Further statistical analysis using regression equations also showed that the IID was slightly wider in female fetuses, but this difference was not statistically significant. Resulting from this analysis, we have arrived at an easy-to-use equation: GA Weeks = (IID mm + 8) ±1 week. We feel this method can be especially applicable in the developing world, where midwives may not have access to software for fetal biometry in their basic handheld ultrasound machines. Even more sophisticated machines may not come with loaded software for obstetrics analysis. There are several limitations to this study, discussed below. We recommend further studies correlating the IID with other biometric parameters.
Highlights
ACCURATE determination of fetal gestational age (GA) is fundamental to obstetric care and is important in a variety of situations
Ultrasound machines in the clinical settings are preloaded with fetal biometric software from leading researchers [2]
These consist of graphs of fetal measurements, biparietal diameter (BPD), femoral length (FL) and several other parameters versus the gestational age
Summary
ACCURATE determination of fetal gestational age (GA) is fundamental to obstetric care and is important in a variety of situations. Precise GA estimation allows for timely delivery or abortion, maternal counseling, fetal management after delivery, accurate interpretation of biochemical and serum tests, and timely scheduling of invasive diagnostic tests such as chorionic villous sampling or amniocentesis. Every measurable structure in the fetal body has been used to calculate gestational age; most commonly used are crown-rump length (CRL), biparietal diameter (BPD), femoral length (FL), head circumference (HC), abdominal circumference (AC) and certain soft tissues. Fetal growth of these measurements is linear in the first half of pregnancy, and generally non-linear in the second half. Statistical graphs and computed software are routinely employed to calculate fetal maturity
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