Geometric Modeling of Human Eyes Based on OCT Image of Anterior Segment and Its Application

Abstract

The aqueous humor flowing in the human eye plays a very important role in maintaining the normal physiological function of the human eye. Once the outflow of aqueous humor is blocked, it will lead to the increase of intraocular pressure, which will lead to glaucoma and other ophthalmic diseases. Therefore, it is of great significance to study the aqueous humor dynamics mechanism of human eyes to explore the physiological structure of human eyes, the pathogenesis and treatment of ophthalmic diseases. In previous studies, most of the geometric models of anterior segment of human eye hydrodynamics are ideal simplified models based on the anatomical data of human eyes, so the simulated results may deviate from the actual situation. In this paper, the OCT image of anterior segment is denoised and segmented by using image processing technology. At the same time, combined with the conventional data of human anatomy, the geometric model of anterior segment is reconstructed, which is closer to the real human eye and has personalized characteristics. On this basis, the flow of aqueous humor in normal eyes was simulated and studied, and the vortex in iris recess was found. The results show that this method can reflect the aqueous humor flow in real eyes more accurately.