Abstract

The film trapping technique, FTT, allows one to investigate the interactions between colloidal particles and a fluid interface that presses them against a flat solid substrate. The method was already applied for measuring the contact angles of micrometer sized latex spheres (Hadjiiski, A.; Dimova, R.; Denkov, N. D.; Ivanov, I. B.; Borwankar, R. Langmuir 1996, 12, 6665.), and the interaction of white blood cells with adsorption layers of antibodies (Patrick, S. M.; An, H.; Harris, M. B.; Ivanov, I. B.; Braunshtein, N. S.; Leonard, E. F. Ann. Biomed. Eng. 1997, 25, 1072. Ivanov, I. B.; Hadjiiski, A.; Denkov, N. D.; Gurkov, T. D.; Kralchevsky, P. A.; Koyasu, S. Biophys. J. 1998, 75, 545.). A new modification of the equipment is now proposed (FTT-gentle), which significantly increases the accessible range of capillary pressures exerted to particles, starting from a virtually zero value. This is particularly important for studying the highly deformable particles (e.g., biological cells) or the oil drops, which...

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