Abstract
Results: The average age of the probands was 22.1. The average SNA, SNB and ANB angles of the probands were 81.2� , 84.1�and -2.9� , respec- tively. A total of 2729 (male 1,354, female 1,375) family members were examined, and the affected ratio of the families was 3.5 % with no significant difference between genders. 45% of families had at least one member with a Class III malocclusion other than the proband. The a ffected ratio of the first-degree relatives (10.9%) was significantly higher than those of the second-degree (3.3%) and third-degree (1.9%) relative s. The affected ratio of the total relatives from the male probands (4.2%) was significantly higher than that of the female probands (2.8%). Heritabilit y (h2 , Falconer' method) was estimated to be 29.8% (0.298±0.059) in first-degree relatives. Conclusion: These results showed the significant influence of mandibular prognathism with relatively low heritability in first-degree relat ives in Korean families of probands, who had undergone orthognathic surgery to correct a skeletal Class III malocclusion.
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