Abstract
Congenital heart disease (CHD) is the most common congenital birth defect. The morbidity and mortality of congenital heart disease rank first among the non-infectious diseases in infants. CHD can be divided into non-syndrome CHD and syndrome CHD. At present, CHD is mainly related to genetic factors, environmental factors and polygenic inheritance. However, the pathogenesis of CHD is complex and has not yet been fully elucidated. The author reviews the research progress of genetic factors in the pathogenesis of CHD, and aims to provide the theoretical basis for the prevention and early diagnosis of CHD. Key words: Heart diseases; Heart defects, congenital; Genetic diseases, inborn; Genes; Chromosomes; Infant
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