Abstract
The current coronavirus 2 (SARS-CoV-2) outbreaks of Coronavirus disease 2019 (COVID-19) pandemic have emphasized the vulnerability of human populations to novel viral pressures, causing an emergent global pandemic and badly impacts on agriculture-environment-health-socio-economy medical-pharmaceutical-science-technology-communication-issues. And India emphasis on okra, Abelmoschus esculentus (L.) Moench Cv. Ankur-40, the ‘Nature’s-Gift to Human-Disease-Free-Healthy-Life’ and the most ‘Economically-Important Number-One Consumption-Vegetable-Crops,’ is damaged by different pathogens like nematodes, causing the root-knot (RK) disease which is easily controlled by different chemical-pesticides, and so it is an urgent need to develop potential epidemiological and biomedical vaccines. The Ultra-High-Diluted Biomedicines (UHDBM) Gall 30C, Gall 200C, and Gall 100C, prepared from Okra Root-Galls (ORG) or Gall MT, applied by foliar spray @ 20 mL/plant each group respectively, are highly effective against the root-knot disease of okra, with increasing fresh-plant growth and fruit production. The UHDBM; Gall 30C, Gall 200C, and Gall 1000-pretreatments are more effective than the untreated ones, and Gall 200C shows the most potential result in all respects. The genetic-effects of UHDBM thought to induce systemic acquired resistance response of the treated plants through the expression of pathogenesis-related (PR)- proteins-genes (22 to 4 numbers), which are more or less similar molecular range (295 kD to 11 kD) of many coronaviruses, and it will responsible for preventing RK and COVID-19 like variant-virus diseases by inducing defense-resistance or increasing innate-immunity, and enriching agricultureenvironment-health-socio-economy-medical-pharmaceutical-science-technology-communication-issues (AEHSEMPSTCI) with the toxic-free world, and it may help to develop best potential new preventive treatments methods or drug or vaccines, in the field of ‘21st Century COVID-19 like Pandemic in the new normal situation in future.
Highlights
IntroductionPandemic problemsThe recent coronavirus 2 (SARS-CoV-2), is just one of the nonillions of viruses on our planet, and scientists are rapidly identifying legions of the most recent species that confronting our National Health Disaster - long-haul Covid-19, outbreaks of Coronavirus disease 2019 (COVID-19) pandemic have emphasized the vulnerability of human populations to novel viral pressures and genome variation of worldwide, causing an emergent global pandemic and badly impacts on agriculture-environment-health-socio-economy medical-pharmaceutical-science-technology-communication-issues, etc [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20].India emphasis on okra (lady finger) for the ‘food security’ which is the most important and crucial aspect of sustainable development in the agricultural sector and the backbone of the economy, but badly impact of the COVID-19 pandemic on food security, agriculture, massive consequences on health and livelihoods of developing countries [21], and it reduced incomes, and disrupted supply chains, chronic and acute hunger was on the rise due to various factors including conflict, socio-economic conditions, natural hazards, climate change, and pests like the locust outbreak compounding this crisis across 23 countries with the other zoonotic diseases remain a recurrent threat
An analysis of root proteins of all 5-groups and nematodes female’s (NF) proteins by electrophoresis and densitometer scanning of all the test Okra Root (OR) and Okra Gall Root (OGR)-proteins show that all the Ultra-High-Diluted Biomedicines (UHDBM); Gall 30, Gall 200C, and Gall 1000C-pretreatments resulted in an increased number of proteins in the roots than uninoculated untreated and inoculated untreated groups; the highest number of root proteins in the UHDBM Gall 200C-pretreated inoculated group is 23, and highest number of the root protein is 19 in the Gall 30C-pretreatment inoculated group, 16 in the Gall 1000C, and 15 in the inoculated untreated group and the lowest number of protein is 11 in the uninoculated untreated group respectively (Table 1 and Figure 2)
The present study clearly showed that the Okra Plants (OP)-growth in terms of fresh biomass of shoot and fruits, and the number of fruits was higher than inoculated untreated groups in all the pretreatment groups of OP treated with the UHDBM; Gall 30, Gall 200C, and Gall 1000C, but reverse in the fresh biomass of roots of inoculated untreated one [4,1419,28-30]
Summary
Pandemic problemsThe recent coronavirus 2 (SARS-CoV-2), is just one of the nonillions of viruses on our planet, and scientists are rapidly identifying legions of the most recent species that confronting our National Health Disaster - long-haul Covid-19, outbreaks of Coronavirus disease 2019 (COVID-19) pandemic have emphasized the vulnerability of human populations to novel viral pressures and genome variation of worldwide, causing an emergent global pandemic and badly impacts on agriculture-environment-health-socio-economy medical-pharmaceutical-science-technology-communication-issues, etc [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20].India emphasis on okra (lady finger) for the ‘food security’ which is the most important and crucial aspect of sustainable development in the agricultural sector and the backbone of the economy, but badly impact of the COVID-19 pandemic on food security, agriculture, massive consequences on health and livelihoods of developing countries [21], and it reduced incomes, and disrupted supply chains, chronic and acute hunger was on the rise due to various factors including conflict, socio-economic conditions, natural hazards, climate change, and pests like the locust outbreak compounding this crisis across 23 countries with the other zoonotic diseases remain a recurrent threat. The recent coronavirus 2 (SARS-CoV-2), is just one of the nonillions of viruses on our planet, and scientists are rapidly identifying legions of the most recent species that confronting our National Health Disaster - long-haul Covid-19, outbreaks of Coronavirus disease 2019 (COVID-19) pandemic have emphasized the vulnerability of human populations to novel viral pressures and genome variation of worldwide, causing an emergent global pandemic and badly impacts on agriculture-environment-health-socio-economy medical-pharmaceutical-science-technology-communication-issues, etc [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20]. On the other hand the pesticides block functional first known gene transfer between plants to insects or animals, which is used in the host’s defenses mechanism for new pest-control strategies and recently in the 31countries of the globe that higher airborne pollen concentrations correlated with increased SARS-CoV-2 infection rates [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30]
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