Abstract
Background and Aims: Angiopoietin-like protein (ANGPTL)8 (A8), together with A3 and A4, coordinate changes in triglyceride (TG) delivery to tissues in response to nutritional status. Plasma A8 levels are associated with indices of glucose and TG metabolism, but the causality of these relationships and the contribution of genetic variants to inter-individual differences in A8 levels has not been investigated.
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