Abstract
Abstract The method of continuous labeling with thymidine-3H and autoradiography of tissue squashes was used to examine patterns of DNA synthesis reflected in the chromosomes of developing embryos of Rana pipiens. At the neurula and tailbud stages there are regions of late-replicating DNA at one or both terminal segments of most chromosomes. This pattern was not present at the blastula or gastrula stages. At any stage the duration of S and G2 are similar for cells in different parts of the body, but the length of G1 and generation time varies.
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