Abstract
ABSTRACTThe proposed general DNA interpretation guidelines provide a comprehensive approach for categorization and interpretation of mixed forensic STR DNA profiles. Mixed DNA profiles occur when there is more than one individual contributing biological material to a sample. The guidelines represent a compilation of methods currently in use by forensic laboratories, along with a discussion of the LSD (Least Squares Deconvolution) objective mathematical approach to interpreting two-person mixtures, as well as the Combined Probability of Inclusion/Probability of Exclusion method. DNA sample features and contexts found in commonly recurring case scenarios permits sorting of profiles into one of six categories. An example profile is interpreted under various scenarios to highlight differences in interpretation dependent on case circumstances. Sorting DNA profiles into categories permits a simplified, scientifically and mathematically sound, conservative interpretation without discarding significant forensic data.
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