Gender specific immune status differences in children and adults

Abstract

Event Abstract Back to Event Gender specific immune status differences in children and adults Julia Lagereva1* 1 Clinical and Diagnostic Centre, Institute of immunology and physiology of the Ural branch of Russian Academy of Sciences, Russia 150 healthy children 7 months-18 years and 45 adults 25-45 years of age balanced by sex were studied to identify gender specific immune status differences dependent from sex hormone concentrations. As result of study it was found that up to 14 years of age the major gender-dependent difference was found among innate immunity phenomena: higher efficacy of phagocytic leucocytes was identified in males. The level of phagocytic activity was correlated with serum progesterone concentration. In older age groups: adolescents 15-18 years and adults the adaptive immunity parameters demonstrated gender-specific differences.Th1 lymphocytes absolute count was increased in male adolescents 15-18 years of age and was correlated with dehydroepiandrosterone sulfate level. Th2 lymphocytes level was significantly higher in females than in males and was correlated with estradiol concentration. IgG and IgM concentrations were higher in adolescent girls and females than in male subjects. Innate and adaptive immunity quantitative factors’ gender-specific differences correlate with changes of sex hormones concentrations. Keywords: immune status, Child Development, Adult, gender differences, T cell subsets Conference: 15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27 Aug, 2013. Presentation Type: Abstract Topic: Adaptive Immunity Citation: Lagereva J (2013). Gender specific immune status differences in children and adults. Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). doi: 10.3389/conf.fimmu.2013.02.00049 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 09 Mar 2013; Published Online: 22 Aug 2013. * Correspondence: Dr. Julia Lagereva, Clinical and Diagnostic Centre, Institute of immunology and physiology of the Ural branch of Russian Academy of Sciences, Ekaterinburg, Russia, anna-lagereva@yandex.ru Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Julia Lagereva Google Julia Lagereva Google Scholar Julia Lagereva PubMed Julia Lagereva Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.