Abstract
This study was designed to analyze the chemical composition of Citrus aurantium Essential Oil (CAEO) peels and to evaluate α-glucosidase inhibition potential, antioxidant and antibacterial activities. According to GC-MS analyses, 37 compounds were identified with limonene was the most abundant (62.2%). Majority of the identified compounds belong to hydrocarbon monoterpenes fraction (75.7%), followed by oxygenated monoterpenes (19.16%). CAEO α-glucosidase inhibition outlined an important activity with IC50 = 10±1 mg/mL. Moreover, antioxidant activity revealed that CAEO exhibited a potent scavenging effect through 2,2-diphenyl-1 picrylhydrazyl radical (DPPH.) (IC50=33.66 µg/mL) and an important ferric ion reducing antioxidant power (FRAP) activity (EC50=98.67 µg/mL). Antimicrobial data demonstrate that CAEO was active against a panel of pathogenic bacteria and that CAEO was able to destroy bacterial cells (bactericidal) according to the MBC/MIC ratios towards Gram+ and Gram- tested strains.
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