Abstract
Background: The conduct of screenings for therapeutic alternatives derived from medicinal plants has emerged as a useful tool for drug discovery and valuable information for further phytotherapeutic studies. Objective: To carry out chemical characterization of ethanol leaf extract of Annona muricata using gas chromatography mass spectroscopy (GC-MS). Materials and method: Apparently healthy leaf samples were taxonomically identified, air-dried and subjected to maceration to obtain ethanol extract stock. GC-MS analysis was utilized to investigate phytochemical composition. Results: The GC-MS analysis spectra was characterized by a total of twenty-six constituents at different retention times which were all identified. Dominant components present included n-Hexadecanoic acid, Oleic Acid and γ-Sitosterol with peak areas 32.60%, 24.35% and 9.10% respectively. Additional constituents were Dodecanoic acid (peak area 4.31%), 13 Octadecenal, (Z) (peak area 2.83%), Bis (2-ethylhexyl) phthalate (peak area 2.31%), Tetradecanoic acid (peak area 2.34%), Trapidil (peak area 2.10%) while others occupied less than 2% peak area. Conclusion: This study suggests that the ethanol leaf extract of A. muricata could possess vital compounds of pharmaceutical and industrial relevance.
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