Abstract
Background: Folk medicine has taken an important place especially in developing countries where limited health services are available. However, the absence of scientific evaluation of medicinal plants may cause serious adverse effects. Objective: To analyze the phytochemical composition of the ethanolic extracts of leaves of Annona muricata using gas chromatography mass spectroscopy (GC-MS). Materials and methods: GC-MS Analysis was used. Results: The GC-MS Analysis revealed 25 constituents of which 12 of the compounds were identified. The major constituents were two unidentified compounds with percentage peak areas of 23.51% and 16.8%. Of the identified compounds, the outstanding in composition were 7-Tetradecenal, (Z) (peak area 9.39%), n-Hexadecanoic acid (peak area 7.12%), Oleyl Alcohol (peak area 6.15%), Phytol (peak area 5.61%), cis, cis, cis-7,10,13-Hexadecatrienal (peak area 4.26%), 2-Pentadecanol (peak area 3.93%), 9,12-Octadecadienoic acid, ethyl ester (peak area 3.21%), 1,2-Benzenedicarboxylic acid, butyl octyl ester (peak area 2.67%), and 1,E- 11,Z-13-Octadecatriene (peak area 2.15%), while the rest had less than 2% composition by peak area. Conclusion: The current study suggests that ethanolic extracts of leaves of Annona muricata are a potent therapeutic agent and paves the way for the development of several treatment regimens based on compounds from this extract.
Highlights
Plant use in treatment of diseases is as old as civilization,[1,2] and complementary medicine is still a major part of habitual treatments of different maladies.[2,3] Generally, complementary medicine has a long history of serving people all over the world.[4,5] In recent times and due to historical, cultural, and other reasons, folk medicine has taken an important place especially in developing countries where limited health services are available
The results obtained from this study represented an important step towards the effective characterization of the secondary class metabolite compounds from this plant using gas chromatography mass spectroscopy (GC-MS) analysis
Phytochemical analysis by GC-MS analysis of the ethanolic extract of leaves of Annona muricata revealed the presence of different fatty acids, heterocyclic compounds, esters among others. 25 peaks were generated
Summary
Plant use in treatment of diseases is as old as civilization,[1,2] and complementary medicine is still a major part of habitual treatments of different maladies.[2,3] Generally, complementary medicine has a long history of serving people all over the world.[4,5] In recent times and due to historical, cultural, and other reasons, folk medicine has taken an important place especially in developing countries where limited health services are available. Results: The GC-MS Analysis revealed 25 constituents of which 12 of the compounds were identified. Conclusion: The current study suggests that ethanolic extracts of leaves of Annona muricata are a potent therapeutic agent and paves the way for the development of several treatment regimens based on compounds from this extract
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