Abstract

All gastrointestinal stromal tumor patients admitted to our institution from 2008 to 2019 were retrospectively reviewed. Demographics, clinical findings, and tumor features, pathological, radiological, and immunohistochemical observations, surgical technique, recurrence, and mortality were documented.

Highlights

  • Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal (GI) tract [1,2]

  • One patient with suspected GIST was diagnosed as well-differentiated liposarcoma according to the pathology report after surgical excision and was excluded from the study

  • Stomach GISTs accounted for 14 tumors (46.7%), small bowel GISTs for 13 (43.3%), esophagus for two (6.7%), and rectum for one tumor (3.3%)

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Summary

Introduction

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal (GI) tract [1,2]. GISTs are rare, with a frequency of approximately 1:100,000 per year [2,3]. Patients with GISTs typically present between 50 and 80 years of age and the majority of tumors are random [4,5]. According to the American Joint Committee on Cancer (AJCC) Staging Manual, the most predominant areas for GISTs are the stomach (60%), small intestine (30%), rectum (3%), colon (1-2%), esophagus (< 1%), and omentum/mesentery (rare) [6]. Patients suspected of GISTs may have multiple symptoms such as early satiety, fatigue, anemia, intraperitoneal hemorrhage, GI bleeding, or abdominal pain. Some have acute abdominal pain that may require emergency medical attention [2,4,5,7]

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