Abstract

Gastroesophageal reflux disease (GERD) is characterized by a large number of clinical manifestations, including asymptomatic and extraesophageal manifestations, so the interest in this nosology of doctors of various specialties is huge. Gastroesophageal reflux disease is considered by modern gastroenterologists as one of the most urgent problems of diseases of the digestive tract. The prevalence of GERD in Western Europe is 10–20%, in Russia – 22,7%, and in Moscow – 23,6% [1]. Studies show that the incidence of this pathology is steadily increasing (annual increase of about 5%). The importance of gastroesophageal reflux disease is determined by its clinical significance, in particular, the possibility of the existence of so-called extraesophageal manifestations, as well as the lack of effectiveness of existing methods of treatment. All this causes close attention of gastroenterologists to the study of pathophysiological and clinical problems of gastroesophageal reflux disease.

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