Abstract
Calliandra portoriscensis is widely used in traditional medicine preparation in South western part of Nigeria for the management of sickle cell crisis and other health challenges. Analysis of the hexane extract of C. portoricensis by GC-MS revealed 14 – methyl methylpentadecanoate as the major component. Other fatty acids/fatty acid methyl esters detected were hexadecanoic acid, methylhexadecanooate, 9 – oxo – methyl nonanoate and some other minor components. The extract was also investigated for preliminary antimicrobial activity using the following pathogenic bacteria Escherichia coli, Staphyloccocus aureus, Salmonella gallinallum, Klebsiela pneumonia, Bacillus subtilis andPseudomonas aeruginosa. The extract was found to be active against S. aureus, E. coli and S. gallinallum, on the other hand it was not active against K. pneumonia, B. subtilis and P. aeruginosa. The results of the GC-MS analysis and the biological assay are discussed. Key words: Calliandra portoricensis, gas chromatography, mass spectrometry, antimicrobial, fatty acid methyl esters.
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