Abstract
Microarrays of lipids containing gangliosides were fabricated on surfaces coated with γ-aminopropylsilane. A fluorescence microarray scanner was used to detect the binding of toxins to these arrays. The specific binding of cholera and tetanus toxins to microspots containing GM1 and GT1b gangliosides, respectively, was demonstrated. These results suggest the possibility of using ganglioside microarrays for multiplexed toxin detection and the screening of compounds that can inhibit toxin binding.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
