Abstract

AbstractWe present some basic concepts of molecular biology and the related open problems.

Highlights

  • Outline of the presentation Introduction Gene Central dogma of molecular biology Protein MicroRNA

  • Open problems Aligning multiple DNA/RNA/Protein sequences (multiple sequence alignment is an NP-hard problem)

  • ` Finding the conserved sequences for drug design (closest substring finding is an NP-complete problem)

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Summary

Introduction

Outline of the presentation Introduction Gene Central dogma of molecular biology Protein MicroRNA Open problems Aligning multiple DNA/RNA/Protein sequences (multiple sequence alignment is an NP-hard problem) ` Finding the conserved sequences for drug design (closest substring finding is an NP-complete problem) ` Sequence analysis of short length RNAs (length margin)

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