Abstract

SummaryFunctional reorganization in the sympathetic nervous system following preganglionectomy has been demonstrated, using the cat as the experimental animal. Skin resistance change in the forepad, in response to stimulation of the ventral roots, was used as an indicator of preganglionic activity. Following interruption of preganglionic pathways to the forepad it was found that preganglionic pathways develop from roots which normally contribute nothing to the forepad.This may offer additional explanation for early relapse following preganglionic section for Raynaud's disease in the hands, and for the fact that operations for this disease are generally more successful in the feet than in the hands.

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