Abstract
Summary Factor B in the properdin system is a heatlabile protein requiring, in addition to properdin, other serum factors, and Mg2+, for formation of a complex with zymosan which preferentially inactivates C3 and later acting components. Factor B is a β-pseudoglobulin which is distinct from C2. Evidence has been presented that factor B is functionally identical to an independently isolated serum protein, C3 proactivator (C3PA). These observations serve both to identify and characterize factor B and, in conjunction with earlier evidence, to establish the properdin system as an alternate pathway to C3 and later acting components, independent of C1, C4 and C2.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
