Abstract
SiroEakova M., M. Koai‰ova, K. Schmidtova, F. Dorko, J. Danko: Functional Morphology of Adrenergic Innervation of Guinea Pig Spleen. Acta Vet. Brno 2001, 71: 159–162. Innervation of the spleen in guinea-pigs was studied. Adrenergic nerve components of the organ were visualized by glyoxylic acid histofluorescence method. The adrenergic nerve components enter the spleen in a common bundle with arteries. In the organ first they form characteristic dense periarterial plexiform arrangements of thicker and thinner nerve profiles, which are especially conspicuous around the aa. centrales running through the white pulp. Then, nerve fibres extend away from these plexuses into the adjacent layers of fibrous trabeculae, further into the marginal layers of periarterial lymphatic sheath (PALS) as well as into the mantle zone of follicles. Several scattered periarterial and solitary nerve profiles can be seen in the marginal sinuses and cords of the red pulp. Innervation of the wall of large and larger veins is relatively richer than in other mammals. In the fibrous capsule of the spleen several specifically fluorescent nerve fibres can also be seen which have an evident connection with trabecular and parenchymal nerves of the organ. Microscopic findings support the notion that adrenergic nerve components participate in the regulation of vascular motility as well as in the regulation of the microenvironment of the organ’s own parenchyma.
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