Abstract

Multifocal epithelial hyperplasia (MEH), also known as verrucae of the oral cavity, focal epithelial hyperplasia, Heck's disease, and multifocal papillomavirus epithelial hyperplasia, is a rare benign oral condition. It is most typically seen in the labial mucosa of younger people and rarely seen in middle-aged patients. Multiple small nodules or papules in the oral cavity, notably on the labial mucosa, buccal mucosa, and tongue, are clinically defined by this lesion. For precise diagnosis needs, clinical history, examination, and histopathologic findings. After months or years, spontaneous regression was commonly recorded; therefore, no treatment was required. Conservative surgical excision can be used for diagnostic and aesthetic reasons and recurrent trauma lesions. We present a very rare oral multifocal epithelial hyperplasia case involving the generalized attached gingiva of the upper and lower jaw in a fully edentulous patient in the Oral Specialized Clinic, Tehran, Iran.

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