Abstract
The polymorphism of the locus FSHRB in intron6-Exon7 of FSHR gene was investigated by PCR-RFLPs in Erhualian, Large White and Landrace×Large White; The association of polymorphism and litter size was analyzed by using SAS. The results showed that 1) the polymorphism of the locus FSHRB was significantly associated with litter size; 2) the total born number (TBN) and number born alive (NBA) of the sows with BB genotype were increased (p<0.05) with additive effects of 1.02-1.42 and 1.04- 1.27 pigs per litter, respectively; 3) among the sows with genotype AA, AB or BB, there was an insignificant difference in born weight and weaning weight. This gene may be an effective potential tool used in conjunction with traditional selection methods. (Asian-Aust. J. Anim. Sci. 2004. Vol 17, No. 2 : 179-182)
Highlights
The follicle stimulating hormone receptor (FSHR) has been suggested as candidate gene for genetic variation in pig reproductive traits, because of the essential role of its product in the physiological mechanisms related to reproductive function, including the initiation and maintenance of qualitatively normal spermatogenesis and follicular development
The gene of PRLR is significantly associated with increasing total number born and number born alive ranged from 0.66 to greater than 1 pig per litter (Vincent et al, 1998)
There is not any research that describes if the mutation in intron6-exon7 of FSHR exists in the pigs and leads to change the litter size
Summary
The results showed that 1) the polymorphism of the locus FSHRB was significantly associated with litter size; 2) the total born number (TBN) and number born alive (NBA) of the sows with BB genotype were increased (p
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