Front Cover: Homemade Solution of NaOD in D 2 O: Applications in the Field of Stilbene‐ d 1 Synthesis (Asian J. Org. Chem. 3/2023)

Abstract

Although NaOD in D2O is a valuable chemical reagent to prepare the deuterium-incorporated products, it costs high. The cover picture shows that the simple and cost-effective preparation of NaOD in D2O from D2O and t-BuONa was accomplished based on the salting-out effect. The homemade NaOD in D2O was used for the one-pot synthesis of mono-deuterated trans-stilbene (stilbene-d1) in the aqueous Horner–Wadsworth–Emmons reaction. The mono-deuterated trans-stilbenes were used to synthesize various deuterated compounds without a loss in the D content. More information can be found in the Research Article by Yoshinari Sawama et al.