Abstract
Droplet-based microfluidics holds enormous potential for transforming the way that many biological screens are performed by affording unprecedented increases in screening throughput and reductions in reagent usage. In this paper, we describe this maturing field and the pioneering work that has laid the foundation for its application to ultrahigh-throughput biological analysis. We begin by introducing the basic elements of the approach and describe the numerous microfluidic components that have been developed for droplet manipulation, with special emphasis on the ones most useful for ultrahigh-throughput analysis. We conclude with a discussion of the first demonstrations of this approach to perform novel, ultrahigh-throughput biological screens.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
