From Muscle Endplate to Brain Synapses: A Short History of Synapses and Agonist-Activated Ion Channels

Abstract

Max Planck Institut fu¨r Medizinische Forschung nists at equilibrium by John Gaddum (e.g., Gaddum,Jahn-Strasse 29 1937) and Heinz Schild (all three of whomheld the Chair69120 Heidelberg of Pharmacology at University College London).Federal Republic of Germany Therewas, of course,nohint in1878that theseobser-vations had anything to do with synaptic transmission.That idea was developed by Henry Dale and his col-