From genetics to cellular physiology. Focus on "Regulation of transferrin-induced endocytosis by wild-type and C282Y-mutant HFE in transfected HeLa cells".

Abstract

hereditary hemochromatosis (HH) is a common inherited disorder of people of Northern European descent, affecting some 1 in 400 people. HH is a disorder of iron metabolism characterized by iron overload in many organs, particularly in the liver, pancreas, heart, and pituitary, leading to multiorgan