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https://doi.org/10.1016/j.tet.2010.12.056
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Cite Journal: Tetrahedron |  Publication Date: Dec 25, 2010 |
 Citations: 29 |
Affiliation: University of Milan
A variety of substituted dihydroisobenzofurans can be easily synthesized in high yields by a one-pot three-component approach starting from o-bromoarylaldehydes, methanol, and terminal alkynes. The reaction occurs through an unprecedented cooperative palladium/base promoted coupling/addition/cyclization sequence.
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