Abstract
ObjectiveTo investigate the correlation between simplified classification and laboratory indicators in patients with acute ischemic stroke, also provide accurate evidences for simplified classification and guide clinical interventions and treatment.MethodsTwo hundred patients with acute ischemic stroke were classified into four types according to the characteristics of Traditional Chinese Medicine syndrome: phlegm‐heat syndrome, phlegm‐dampness syndrome, qi deficiency syndrome, and yin deficiency syndrome. The differences between the types of syndromes and the correlation between laboratory indicators and syndromes were analyzed.ResultsAmong the 200 patients with acute ischemic stroke, there were significant differences in the level of low‐density lipoprotein (LDL‐C) (p < .05) between patients with phlegm‐heat syndrome and other three types. There were significant differences in the levels of homocysteine (HCY) and fibrinogen (Fib) between patients with yin deficiency syndrome and other three types (p < .05). In addition, there were statistically significant differences in blood glucose (Glu), glycosylated hemoglobin (HBA1c), and total cholesterol (CHO) between phlegm‐heat syndrome and qi deficiency syndrome (p < .05). There were significant differences in the levels of Glu, HBA1c, D‐2 polymer (D‐D), and C‐reactive protein (CRP)s between patients with phlegm‐heat syndrome and phlegm‐dampness syndrome (p < .05). There were statistically significant differences in the levels of CRP and urea nitrogen between patients with yin deficiency syndrome and phlegm‐dampness syndrome and qi deficiency syndrome (p < .05).ConclusionsThe four‐type simplified classification of Integrated TCM and Western medicine in acute ischemic stroke has specific laboratory data to support. Simplified classification with TCM treatment and intervention of different patients improves the survival and treatment, which is an innovative, easy‐to‐master clinical diagnosis and treatment model.
Highlights
Acute ischemic stroke is one of the major disabling and lethal diseases in the world that has become the first cause of death in China with its increasing incidence and younger trend (Chen, 2008)
Based on years of clinical practice, the team of integrated Chinese and Western medicine in the Department of Neurology of Xuanwu Hospital has simplified the classification of acute ischemic stroke into four types: phlegm‐heat syndrome, phlegm‐dampness syndrome, qi deficiency syndrome, and yin de‐ ficiency syndrome, on which condensed the prescriptions of the Chinese medicine agreement corresponding to the syndrome type: Tanhuofang, Tanshifang, Qixufang, and Yinxufang, which have achieved good clinical results
Simplified classification and laboratory indicators analyzing of 200 patients with acute ischemic stroke admitted from February 2017 to December 2017 in Department of Neurology, Xuanwu Hospital of Capital Medical University are reported as follows
Summary
Acute ischemic stroke is one of the major disabling and lethal diseases in the world that has become the first cause of death in China with its increasing incidence and younger trend (Chen, 2008). An in‐depth study of TCM syndromes and inte‐ grated into Western diagnostics has been proposed, leading to a new medical model diagnosis and treatment program (Jiang et al, 2012). The correlation between the simpli‐ fied classification and laboratory indicators will provide objective evidence for the classification and provide new ideas for the man‐ agement of patients with acute ischemic stroke and promote the new diagnosis and treatment models. Simplified classification and laboratory indicators analyzing of 200 patients with acute ischemic stroke admitted from February 2017 to December 2017 in Department of Neurology, Xuanwu Hospital of Capital Medical University are reported as follows
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