Abstract

Abstract Disclosure: R.B. Boghossian: None. G.F. Maselli: None. C.C. Lopes: None. C.A. Vasconcellos: None. C.A. Parente: None. D.D. Ferreira: None. J.C. Garcia: None. L.M. Guimarães: None. E.S. Muxfeldt: None. C.P. Damião: None. Background: Obesity is increasing in younger populations, and is associated with a high cardiovascular (CV) risk, however, it is not clear whether metabolically healthy obesity (MHO) may have a lower CV risk or if it is just an earlier stage of the disease. Objective: To evaluate the prevalence and cardiovascular (CV) risk factors associated with metabolically healthy obesity (MHO) in a young population assisted by a Family Health Care unit in a large urban center. Design and Methods: A cross-sectional population study for CV risk assessment in adults aged 20-50 years old from a Family Health Care unit. Demographic, anthropometric data and CV risk factors were recorded. All underwent office blood pressure (BP) measurements, laboratory evaluation (lipid and glycidic profile), Home Blood Pressure Monitoring (HBPM), and bioimpedance. Obesity was defined as a body mass index (BMI) > 30 kg/m2 and MHO are those who have less than 3 of the following criteria for metabolic syndrome: office BP higher or equal to 130 x 85 mmHg, hypertension, fasting blood sugar higher or equal to 100 mg/dL, HDL < 40 mg/dL (men) and 50 mg/dL (women), triglycerides >150 mg/dL and waist circumference > 102 cm (men) and > 88 cm (women). Results: A total of 726 individuals were evaluated (60% female; mean age 37 ± 9 years). The prevalence of obesity was 24.9%, of which 73.4% were classified as MHO. Obeses are older, with a higher prevalence of physical inactivity (51% vs 42%, p=0.03), hypertension (44% vs 19%, p<0.001), and diabetes (10% vs 2%, p=0.001) with higher office and home blood pressure. MHO compared to unhealthy ones are significantly younger and smoke less. Despite being obese, they have lower waist circumference (102 vs 110 cm, p=0.03), with lower office and home BP. There is no significant difference in relation to corporal composition. Conclusion: MHO was more prevalent in this young population and seems to have a lower CV risk, however it is not clear whether these younger and less obese individuals are only at an earlier stage of the disease. Perhaps the CV diseases onset is postponed for a few years. Even so, these individuals should not be excluded from public health policies as a form of primary prevention Presentation: Friday, June 16, 2023

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