Abstract

This study was conducted to assess the incidence of abnormalities of ventricular depolarization in sinus rhythm after repair of tetralogy of Fallot and their relation to spontaneous ventricular arrhythmias. Forty-four patients were studied, 10 before surgery (mean age 6.9 years) and 34 after repair (mean age 8.1 years, mean age at surgery 6.5 years, mean interval between surgery and evaluation 11 months). Evaluation was performed by means of body surface and intracavitary signal-averaging techniques, by recording local right ventricular (RV) electrograms at several sites and by 24-hour Holter monitoring (n = 28). No electrophysiologic abnormality was observed in children before surgery. Ventricular late potentials were detected in 18 patients (53%) after repair. Body surface detection of ventricular late potentials was frequently masked by the postoperative right bundle branch block pattern. Local RV electrograms were fractionated in 11 cases (32%) (mean duration 103 ± 33 ms), most often in the RV outflow tract (n = 9), but no relation was found between fragmentation of RV electrograms and the presence of ventricular late potentials. Spontaneous ventricular arrhythmias occurred in 12 children after repair (43%), but were complex in only 4 patients (14%). There was no correlation between spontaneous ventricular arrhythmias and the presence of ventricular late potentials, presence of fractionated RV electrograms, presence of a proximal right bundle branch block or postoperative hemodynamic status. In conclusion, ventricular late potentials and fractionated RV electrograms during sinus rhythm are common after repair of tetralogy of Fallot (71 % of the cases) but are absent before surgery. In this short-term postoperative study no relation was found between these electrophysiologic abnormalities and the occurrence of spontaneous ventricular arrhythmias, and long-term follow-up studies are needed to assess their prognostic significance.

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