FREQUENCY OF PERIPROCEDURAL MYOCARDIAL INFARCTION IN PATIENTS UNDERGOING ELECTIVE PERCUTANEOUS CORONARY INTERVENTION

Abstract

Objective: To determine the frequency of periprocedural myocardial infarction in patients undergoing elective percutaneous coronary intervention. Methodology: In this study 100 patients with an indication for elective PCI admitted in CCU at civil hospital Karachi were studied. Cardiac biomarker measurements were scheduled before PCI and 6 hours after PCI, with subsequent serial measurements for relevant biomarker increases or complaints until peak increase was established. We used the PMI definition from the third universal definition of MI: creatine kinase (CK-MB )3 times upper limit of normal. All statistical analyses were performed with SPSS 12.0 Frequency was calculated using chi-square. Results: Patients in the study population had more diabetes mellitus (29% vs 16%, p< 0.001), hypertension (61% vs 51%, p <0.001), hypercholesterolemia (66% vs 54%, p <0.001), and family history of coronary artery disease (57% vs 50%, p < 0.01) Of the study population (29%) had a history of diabetes mellitus. PMI occurred in 5% of the study population. PMI occurred in five patients, 1 with 3 stents, 2 with 2 stents and 1 with 3 stents. Conclusion: Frequency of PMI is low and is directly correlated with number of stents implanted. This needs to be confirmed in larger studies.