Abstract

Frequency of neuropathic pain and its impact on functional status in primary knee osteoarthritis patients

Highlights

  • Osteoarthritis (OA) is the most common form of joint disorder, with knee OA being a leading cause of disability among older adults globally(1)

  • BMI, and other WOMAC subscale were not found to be significantly correlated with Douleur Neuropathique en 4 (DN4) score

  • Knee OA has been considered the archetypal model of inflammatory or nociceptive pain (9), it is increasingly apparent that people with knee OA may present with different pain phenotypes

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Summary

Introduction

Osteoarthritis (OA) is the most common form of joint disorder, with knee OA being a leading cause of disability among older adults globally(1). It causes significant morbidity in elderly individuals, and its age of onset is gradually decreasing(2). Discordance between radiographic and pain severity in people with OA has led researchers to investigate the existence of other pain mechanisms to explain this discrepancy(6). Both peripheral and central mechanisms found to contribute to OA pain(5).

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