Abstract

Frequency of neuropathic pain and its impact on functional status in primary knee osteoarthritis patients

Highlights

  • Osteoarthritis (OA) is the most common form of joint disorder, with knee OA being a leading cause of disability among older adults globally[1]

  • Knee OA has been considered the archetypal model of inflammatory or nociceptive pain[9], it is increasingly apparent that people with knee OA may present with different pain phenotypes

  • It is recognized that some individuals with knee OA exhibit features of neuropathic pain[9]

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Summary

Introduction

Osteoarthritis (OA) is the most common form of joint disorder, with knee OA being a leading cause of disability among older adults globally[1]. It causes significant morbidity in elderly individuals, and its age of onset is gradually decreasing[2]. Neuropathic mechanisms are considered to play a role in development of pain in knee osteoarthritis (OA). Pain severity was assessed by Numerical rating scale (NRS), neuropathic pain was assessed by Douleur Neuropathique en 4 (DN4) questionnaire and functional status was assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale. Neuropathic pain is a factor that increases pain and disability and disrupts functional status in osteoarthritis patients.

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