Abstract

The aim of present study was to investigate the in vitro antioxidant potential and total extractive yield of Mussaenda luteola Delile leaves. Antioxidant activity was assessed by using 2,2- diphenyl-1-picryl-hydrazyl (DPPH• ) assay, reducing power activity and [2,2’-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid)] ABTS•+ assay. Here ascorbic acid (ASA) and rutin were used as standard antioxidants. The results of the study indicates that the chloroform extracts of the leaf of Mussaenda luteola possesses significant scavenging activity against DPPH• (17.56) and reducing power activity (0.759) at 700nm absorbance. The ethanolic leaf extracts holds high free radical scavenging activity (ABTS•+) at 735nm (94.59). The free radical scavenging and antioxidant activities may be attributed to the presence of adequate phenolic and flavonoid compounds. The ethanolic leaf extract of M. luteola yields maximum extractive yield percentage (37.08%). This study revealed that the leaf extracts of Mussaenda luteola has demonstrated significant antioxidant activity.

Highlights

  • Natures are sources of medicinal agents and produces enormous number of new drugs based on their use in traditional medicine

  • This study revealed that the leaf extracts of Mussaenda luteola has demonstrated significant antioxidant activity

  • For the present study M. luteola leaves were collected for total extractive yield and antioxidant activities

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Summary

Introduction

Natures are sources of medicinal agents and produces enormous number of new drugs based on their use in traditional medicine. Traditional medicines are found to be fundamentally preventive, protective, nutritive and curative. They are safe and harmless and could treat patients without side effects. While finding the prior plants with high potent medicinal values, it can be used to treat various ailments. In such case we could prevent and save the present and future generations from health hazards, new novel diseases and various unknown health deteriorating ailments. Some species of Mussaenda have been used in Chinese and Fijian traditional medicine

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