Abstract
THE possibility of using gel electrophoresis for the fractionation of RNA was first well illustrated by Tsanev1, who obtained excellent separation of RNA main fractions, as well as minor components, by agar gel electrophoresis. More recently, Loening2 used the polyacrylamide gel electrophoresis recommended by Richards et al.3 and was able to obtain a very good separation of the two ribosomal fractions and transfer RNA in 2.2 per cent and 2.6 per cent gels and a separation of 4S and 5S RNA in 5 per cent and 7 per cent gels; this latter fractionation is not possible by agar gel electrophoresis.
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