Abstract
Mass spectrometry is essentially a technique for weighing molecules. Mass spectrometry is based upon the motion of a charged particle, called an ion, in an electric or magnetic field. Mass spectrometry relies on the formation of gas-phase ions (positively or negatively charged) that can be isolated electrically (or magnetically) based on their mass-to-charge ratio ( m/z ). Where as in Fourier transform ion cyclotron mass resonance spectroscopy(FTICR-MS) the m/z ratio measurement of an ion is based upon the ion's motion or cyclotron frequency in a magnetic field. Ions are detected by passing near detection plates and thus differently from other mass detectors/analysers in which ions are hitting a detector (at different times or places),The ions are trapped in a magnetic field combined with electric field perpendicular to each other (Penning trap). They are excited to perform a cyclotron motion. The cyclotron frequency depends on the ratio of electric charge to mass (m/z) and strength of the magnetic field.This spectrometric analysis can provide important information about the analytes, including their structure, purity, and composition.
Highlights
Kotra et al /2012 cell’s two end-cap electrodes
The trapped ions When a magnet or electric field is applied, the describe a circular orbit with a characteristic positive charged fragments travelling in a straight orbital frequency, known as the ion path, travels in a carved path, when they cyclotron frequency ωc where, travel in carved path under the influence of magnetic field, the fragments are separated into different masses because of radius of
On applying an r – radius of path excitation signal with a frequency ωc, the ions mass α will absorb energy and the ion ensemble will Since e = 1 describe a coherent cyclotron motion with a larger In recent years, FT-ICR has proven itself to be an orbital radius
Summary
The differentially pumped, oil-free, ultra-high vacuum passive shielding surrounding the magnet system capable of sustaining a base pressure of consists of an iron cage with a weight of 11 below 5 × 10-9 mbar using either turbomolecular metric tonnes. The ESI source is surface of the magnet shield and
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