FORMULATION OF CINNAMON BARK ESSENTIAL OIL GEL AS MOSQUITO REPELLENT

Dhadhang Wahyu Kurniawan,Gunawan Adi Wibowo,Vidya Nur Agustina,Muhammad Zaenuri Syamsu Hidayat,Sunarto Sunarto

doi:10.22159/ijap.2022v14i1.43034

Dhadhang Wahyu Kurniawan, Gunawan Adi Wibowo + Show 3 more

Open Access

https://doi.org/10.22159/ijap.2022v14i1.43034

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Abstract

Objective: The purpose of this research is to prepare a cinnamon bark essential oil gel preparation, determines the physical characteristic and physical stability during storage, and examines the activity of mosquito repellent from the best gel preparation. Methods: The formulations of gel were made with variations in the concentration of Carbopol 940 (0.5%, 1.5%, and 2%) contain 1% of cinnamon bark essential oil. The gel evaluated physical characteristics and physical stability. The parameters of organoleptic, homogeneity, and pH are analyzed descriptive, while the viscosity, the spreadability, and the gel adhesion were analyzed using one-way ANOVA at the level of confidence of 95%. The best gel tested its effectiveness as compared to the negative control and product innovator (which used DEET as an active compound) as a positive control. The activity of repellent was determined by an Aedes aegypti mosquito for 6 h with 2 hands respondents. The effectiveness of repellent protection is calculated by the percentage of protection power. Results: The studies showed that all the gel preparations qualified the organoleptic, homogeneity, and pH parameters. The viscosity, gel adhesion, and spreadability are also stable during storage. Conclusion: Based on the results, the best gel is the formula I which has mosquito repellent activity effective for 6 h like DEET.

Highlights

Indonesia is a tropical country rich in various types of insects that provide benefits, but some are detrimental [1]
The materials used in this study were the main materials, namely cinnamon bark essential oil obtained from Lansida Group, Yogyakarta, Indonesia
Formulation of cinnamon bark essential oil gel Formulation of the Cinnamon bark essential oil gel for the experiments could be seen in table 1

Summary

Introduction

Indonesia is a tropical country rich in various types of insects that provide benefits, but some are detrimental [1]. One of the insect groups that harm humans is mosquitoes which are vectors of various diseases, including malaria, dengue hemorrhagic fever (DHF), and chikungunya [2]. Some efforts are applied such as by using mosquito repellent sprays (spray), mosquito coils (coil), and repellent preparations are generally used [3]. Repellents had been marketed at this time are repellent made of chemical containing the active ingredient N, N-dietil-m-toluamid (DEET) [4]. DEET has good repellency because it can provide a period of protection ranging from 2 to 8 h depending on the concentration in the product [5]. The use of DEET potentiates endanger health by having various side effects such as hypersensitivity, irritation, and urticaria and in the long term use can cause cancer [6]

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Results

Conclusion