Formulation and standardization of Peetha Saireyaka tablet – A novel Ayurvedic drug to combat Chronic tonsillitis in children

Abstract

Introduction: Peetha Saireyaka tablet (PST) is a herbal formulation widely used in Ayurvedic clinical practice with multi fold benefits, specifically to combat chronic tonsillitis in children. There is no work on record on formulation and standardization aspect of herbal drug, Peetha Saireyaka tablet. This paper highlights the preparation, physico-chemical characterization, TLC and HPTLC densitogram profiling of Peetha Saireyaka tablet which can be applied for authentication of this herbal formulation. Methods: The roots of Peetha Saireyaka (Barleria prionitis Linn.) were authenticated botanically. The tablets were prepared at certified pharmacy and subjected for detailed physico-chemical and HPTLC analyses. Results: Set of standardization parameters were derived for Peetha Saireyaka tablet by physico-chemical characterization. The tests proposed would serve as diagnostic parameters for the identity of this herbal formulation. HPTLC fingerprint profile which can serve as a fingerprint for the identification of the formulation has been obtained. Conclusion: The proposed method of making tablet from roots of Peetha Saireyaka (Barleria prionitis Linn.) will aid in yielding concentrated medicament with the same efficacy as per the classically proposed drug dosage at lower dose. Standards for the herbal formulation has been developed for the quality check of the formulation.