Abstract
The present work is to study the effect of various superdisintegrants on drug (Albendazole) by direct compression methods. The tablets were prepared by four super disintegrants, e.g; sodium starch glycolate, cross carmellose, cross povidone and L- subsituated hydroxyl propyl cellulose. The blend was examined for angle of repose, bulk density, tapped density, compressibility index, and hausner ratio. The tablets were evaluated for hardness, drug content and friability were found satisfactory. Albendazole is a bitter in taste. To prevent bitter taste of the drug formulated with a sweetener (Aspartame), a mannitol-based diluent. Taste evaluation was done by panel tasting.
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