Formulation and Evaluation of Polyherbal Emulgel

Abstract

The foible of allopathic medicines has resulted in adopting herbal plants that have been proven cost-effective with fewer adverse effects. Thus, the evaluation of the potential of herbal plants for the formulation of innovative dosage forms has resulted in the cure of various disease conditions. Thus, in context, the main aim of this work was to formulate the topical emulgel using herbal extracts of Ocimum sanctum, Rubia cordifolia, Glycyrrhiza glabra and Punica granatum. Emulgel was prepared by use of 23 factorial designs and the influence of the type of the gelling agent on viscosity and drug release from the prepared emulgel was investigated. The results found that the EG7 formulation was the optimized batch with pH of 6.3±0.02, viscosity of 5998.7±1.2 mPas, drug release of 89.75± 3.5% and in terms of stability. The results indicated the emulgel formulations were successful concerning all of the parameters.