Formulation and Evaluation of Phytosomes of Pterocarpus santalinus Extract

Abstract

Abstract: Novel drug delivery system (NDDS) phytosomes were prepared by complexing phospholipids: Cholesterol and Leaves extract of Pterocarpus santalinus can act as molecular adhesive to bind components together. Their ability to penetrate lipid-rich biomembranes and shield the essential components of the herbal extract from being destroyed by digestive secretions and gut bacteria increases bioavailability. The bioavailability of the herbal formulation is increased by phytosomes' ability to distribute the standardised plant extracts and phytoconstituents through different routes of drug administration methods. The present study directed toward the development and evaluation of phytosomes of Pterocarpus santalinus. Through an in-vitro dissolution study, the produced complex's physicochemical characteristics were examined. The outcome demonstrated that there was no formation of a novel chemical between the hydroalcoholic extract and the phospholipids in the Methanolic extract-phospholipid complex. Prepared Pterocarpus santalinus extract phytosomes showed better bioavailability.